Poland | Scientists from the Jagiellonian University have discovered new biological mechanisms that could help combat antibiotic-resistant bacteria, one of the most serious threats to modern medicine.The research focuses on bacteriophages, viruses that naturally infect and destroy bacteria without harming humans or animals. These viruses have evolved over billions of years and are now being studied as a potential alternative to traditional antibiotics.Researchers found that bacteriophages use more complex methods to attack bacteria than previously believed. In addition to enzymes that break down bacterial defenses, they also use proteins that modify bacterial surface structures, allowing them to penetrate protective layers more effectively.The study, led by Dr. Rafał Mostowy from the Małopolska Centre of Biotechnology at the Jagiellonian University, used advanced computational methods and machine learning to analyze viral genetic material hidden within bacterial DNA.According to the researchers, each newly discovered mechanism could lead to the development of targeted therapies against drug-resistant infections. This is particularly important as bacteria continue to evolve resistance to existing antibiotics.The findings, published in PLOS Biology, highlight the growing importance of bacteriophage research in developing future medical treatments and strengthening global health defenses against infectious diseases.
Source: Jagiellonian University
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